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In Vivo Roles of Conjugation with Glutathione and O(6)-Alkylguanine DNA-Alkyltransferase in the Mutagenicity of the bis-Electrophiles 1,2-Dibromoethane and 1,2,3,4-Diepoxybutane in Mice
[Image: see text] Several studies with bacteria and in vitro mammalian systems have provided evidence for the roles of two thiol-based conjugation systems, glutathione (GSH) transferase and O(6)-alkylguanine DNA-alkyltransferase (AGT), in the bioactivation of the bis-electrophiles 1,2-dibromoethane...
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| Autors principals: | , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2013
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3889014/ https://ncbi.nlm.nih.gov/pubmed/24191644 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/tx4003534 |
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