IPS-1 Signaling Has a Non-Redundant Role in Mediating Antiviral Responses and the Clearance of Respiratory Syncytial Virus

The cytosolic RNA helicases melanoma differentiation-associated gene 5 (MdA5) and retinoic acid-inducible gene-I (RIG-I) and their adaptor IFNβ promotor stimulator (IPS-1) have been implicated in the recognition of viral RNA and the production of type I interferon (IFN). Complementing the endosomal...

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Hlavní autoři: Demoor, Tine, Petersen, Bryan C, Morris, Susan, Mukherjee, Sumanta, Ptaschinski, Catherine, De Almeida Nagata, Denise E, Kawai, Taro, Ito, Toshihiro, Akira, Shizuo, Kunkel, Steven L, Schalle, Matthew A, Lukacs, Nicholas W
Médium: Artigo
Jazyk:Inglês
Vydáno: 2012
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3888965/
https://ncbi.nlm.nih.gov/pubmed/23136205
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1201763
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