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Activation of antibody Fc function by antigen-induced conformational changes.

IgM antibody directed against the pheny-beta-lactoside hapten was examined for its capacity to fix complement in the presence of the hapten, monohapten-substituted antigen, and multihapten-substituted antigen. Hapten was found to have no effect; monovalent antigen induced an excellent response which...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Autores principales: Brown, J C, Koshland, M E
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 1975
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Acceso en línea:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC388886/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1061094/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.72.12.5111
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