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Activation of antibody Fc function by antigen-induced conformational changes.

IgM antibody directed against the pheny-beta-lactoside hapten was examined for its capacity to fix complement in the presence of the hapten, monohapten-substituted antigen, and multihapten-substituted antigen. Hapten was found to have no effect; monovalent antigen induced an excellent response which...

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Bibliographic Details
Main Authors: Brown, J C, Koshland, M E
Format: Artigo
Language:Inglês
Published: 1975
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC388886/
https://ncbi.nlm.nih.gov/pubmed/1061094
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