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Protective Effects of Polyamine Depletion in Mouse Models of Type 1 Diabetes: Implications for Therapy
The underlying pathophysiology of type 1 diabetes involves autoimmune-mediated islet inflammation, leading to dysfunction and death of insulin-secreting islet β cells. Recent studies have shown that polyamines, which are essential for mRNA translation, cellular replication, and the formation of the...
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| Autores principales: | , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2013
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3888834/ https://ncbi.nlm.nih.gov/pubmed/23846959 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00726-013-1560-7 |
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