Deoxyhypusine Synthase Promotes Differentiation and Proliferation of T Helper Type 1 (Th1) Cells in Autoimmune Diabetes

In type 1 diabetes, cytokines arising from immune cells cause islet β cell dysfunction even before overt hyperglycemia. Deoxyhypusine synthase catalyzes the crucial hypusine modification of the factor eIF5A, which promotes the translation of a subset of mRNAs involved in cytokine responses. Here, we...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Colvin, Stephanie C., Maier, Bernhard, Morris, David L., Tersey, Sarah A., Mirmira, Raghavendra G.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2013
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3868737/
https://ncbi.nlm.nih.gov/pubmed/24196968
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.473942
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados