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Macrophages block insulin action in adipocytes by altering expression of signaling and glucose transport proteins

Obesity leads to a proinflammatory state with immune responses that include infiltration of adipose tissue with macrophages. These macrophages are believed to alter insulin sensitivity in adipocytes, but the mechanisms that underlie this effect have not been characterized. We have explored the inter...

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Bibliografiske detaljer
Main Authors: Lumeng, Carey N., Deyoung, Stephanie M., Saltiel, Alan R.
Format: Artigo
Sprog:Inglês
Udgivet: 2006
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3888778/
https://ncbi.nlm.nih.gov/pubmed/16926380
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00284.2006
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