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Macrophages block insulin action in adipocytes by altering expression of signaling and glucose transport proteins

Obesity leads to a proinflammatory state with immune responses that include infiltration of adipose tissue with macrophages. These macrophages are believed to alter insulin sensitivity in adipocytes, but the mechanisms that underlie this effect have not been characterized. We have explored the inter...

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Detalhes bibliográficos
Main Authors: Lumeng, Carey N., Deyoung, Stephanie M., Saltiel, Alan R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3888778/
https://ncbi.nlm.nih.gov/pubmed/16926380
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00284.2006
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