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A structural gene mutation affecting the regulatory subunit of cyclic AMP-dependent protein kinase in mouse lymphoma cells.

Compared to the wild-type parental line of S49 mouse lymphoma cells, intact cells of a mutant line (kin.A) are 10-fold less sensititive to biologic effects of exogenous cyclic adenosine 3':5'-monophophosphate (cAMP), such as induction of cAMP phosphodiesterase, cell cycle-specific growth inhibition,...

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Bibliografiske detaljer
Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Hochman, J, Insel, P A, Bourne, H R, Coffino, P, Tomkins, G M
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1975
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC388873/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/174091/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.72.12.5051
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