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Reversion of an S49 cell cyclic AMP-dependent protein kinase structural gene mutant occurs primarily by functional elimination of mutant gene expression.

The regulatory subunits of cyclic AMP (cAMP)-dependent protein kinase from a dibutyryl cAMP-resistant S49 mouse lymphoma cell mutant, clone U200/65.1, and its revertants were visualized by two-dimensional polyacrylamide gel electrophoresis. Clone U200/65.1 co-expressed electrophoretically distinguis...

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Autors principals: van Daalen Wetters, T, Coffino, P
Format: Artigo
Idioma:Inglês
Publicat: 1983
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC368529/
https://ncbi.nlm.nih.gov/pubmed/6300660
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