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Reversion of an S49 cell cyclic AMP-dependent protein kinase structural gene mutant occurs primarily by functional elimination of mutant gene expression.

The regulatory subunits of cyclic AMP (cAMP)-dependent protein kinase from a dibutyryl cAMP-resistant S49 mouse lymphoma cell mutant, clone U200/65.1, and its revertants were visualized by two-dimensional polyacrylamide gel electrophoresis. Clone U200/65.1 co-expressed electrophoretically distinguis...

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Bibliographic Details
Published in:Mol Cell Biol
Main Authors: van Daalen Wetters, T, Coffino, P
Format: Artigo
Language:Inglês
Published: Taylor & Francis 1983
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC368529/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6300660/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.3.2.250-256.1983
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