Concordance Between CYP2D6 Genotypes Obtained From Tumor-Derived and Germline DNA

Formalin-fixed, paraffin-embedded tumors (FFPETs) are a valuable source of DNA for genotype association studies and are often the only germline DNA resource from cancer clinical trials. The anti-estrogen tamoxifen is metabolized into endoxifen by CYP2D6, leading to the hypothesis that patients with...

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Detalhes bibliográficos
Main Authors: Rae, James M., Regan, Meredith M., Thibert, Jacklyn N., Gersch, Christina, Thomas, Dafydd, Leyland-Jones, Brian, Viale, Giuseppe, Pusztai, Lajos, Hayes, Daniel F., Skaar, Todd, Van Poznak, Catherine
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2013
Assuntos:
Brief Communication
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3888280/
https://ncbi.nlm.nih.gov/pubmed/23958736
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jnci/djt204
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