ΔFosB induction correlates inversely with CB(1) receptor desensitization in a brain region- dependent manner following repeated Δ(9)-THC administration

Repeated Δ(9)-tetrahydrocannabinol (THC) administration produces desensitization and downregulation of cannabinoid type 1 receptors (CB(1)Rs) in the brain, but the magnitude of these adaptations varies among regions. CB(1)Rs in the striatum and its output regions exhibit the least magnitude and slow...

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Autores principales: Lazenka, Matthew F., Selley, Dana E., Sim-Selley, Laura J.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2013
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3888085/
https://ncbi.nlm.nih.gov/pubmed/24090766
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuropharm.2013.09.019
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