טוען...

Delta FosB and AP-1-mediated transcription modulate cannabinoid CB(1) receptor signaling and desensitization in striatal and limbic brain regions

Repeated Δ(9)-tetrahydrocannabinol (THC) administration produces cannabinoid type 1 receptor (CB(1)R) desensitization and downregulation, as well as tolerance to its in vivo pharmacological effects. However, the magnitude of CB(1)R desensitization varies by brain region, with CB(1)Rs in the striatum...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
Main Authors: Lazenka, Matthew F., David, Bethany G., Lichtman, Aron H., Nestler, Eric J., Selley, Dana E., Sim-Selley, Laura J.
פורמט: Artigo
שפה:Inglês
יצא לאור: 2014
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC4162133/
https://ncbi.nlm.nih.gov/pubmed/25093286
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcp.2014.07.024
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