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ΔFosB induction correlates inversely with CB(1) receptor desensitization in a brain region- dependent manner following repeated Δ(9)-THC administration
Repeated Δ(9)-tetrahydrocannabinol (THC) administration produces desensitization and downregulation of cannabinoid type 1 receptors (CB(1)Rs) in the brain, but the magnitude of these adaptations varies among regions. CB(1)Rs in the striatum and its output regions exhibit the least magnitude and slow...
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| Главные авторы: | , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2013
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3888085/ https://ncbi.nlm.nih.gov/pubmed/24090766 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuropharm.2013.09.019 |
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