A New Anti-c-Met Antibody Selected by a Mechanism-Based Dual-Screening Method: Therapeutic Potential in Cancer

c-Met, the high affinity receptor for hepatocyte growth factor (HGF), is one of the most frequently activated tyrosine kinases in many human cancers and a target for cancer therapy. However, inhibitory targeting of c-Met with antibodies has proven difficult, because most antibodies have intrinsic ag...

Descrición completa

Gardado en:
Detalles Bibliográficos
Main Authors: Oh, Young Mi, Song, Yun-Jeong, Lee, Saet Byoul, Jeong, Yunju, Kim, Bogyou, Kim, Geun Woong, Kim, Kyung Eun, Lee, Ji Min, Cho, Mi-Young, Choi, Jaehyun, Nam, Do-Hyun, Song, Paul H, Cheong, Kwang Ho, Kim, Kyung-Ah
Formato: Artigo
Idioma:Inglês
Publicado: Korea Society for Molecular and Cellular Biology 2012
Assuntos:
Articles
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3887825/
https://ncbi.nlm.nih.gov/pubmed/23180291
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10059-012-0194-z
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares