LIME Mediates Immunological Synapse Formation through Activation of VAV

Lck Interacting Membrane protein (LIME) was previously characterized as a transmembrane adaptor protein mediating TCR-dependent T cell activation. Here, we show that LIME associates with Vav in response to TCR stimulation and is required for Vav guanine nucleotide exchange factor (GEF) activity for...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Son, Myoungsun, Park, Inyoung, Lee, Ok-Hee, Rhee, Inmoo, Park, Changwon, Yun, Yungdae
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Korea Society for Molecular and Cellular Biology 2012
Gaiak:
Articles
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3887804/
https://ncbi.nlm.nih.gov/pubmed/22395814
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10059-012-0011-8
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