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Constitutive Activation of Smoothened Leads to Impaired Developments of Postnatal Bone in Mice
Sonic hedgehog (Shh) signaling regulates patterning, proliferation, and stem cell self-renewal in many organs. Smoothened (Smo) plays a key role in transducing Shh signaling into the nucleus by activating a glioma family of transcription factors; however, the cellular and molecular mechanisms underl...
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| Главные авторы: | , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Korea Society for Molecular and Cellular Biology
2012
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3887766/ https://ncbi.nlm.nih.gov/pubmed/22983747 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10059-012-0186-z |
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