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Simvastatin Promotes Osteogenic Differentiation of Mouse Embryonic Stem Cells Via Canonical Wnt/β-Catenin Signaling
Simvastatin, an inhibitor of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase, has been known to reduce cholesterol biosynthesis. However, recent studies demonstrate that simvastatin shows diverse cholesterolindependent functions including cellular differentiation. In this study, we investi...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Korean Society for Molecular and Cellular Biology
2011
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3887698/ https://ncbi.nlm.nih.gov/pubmed/22058016 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10059-011-0107-6 |
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