Context-specific BAFF-R signaling by the NF-κB and PI3K pathways

BAFF is a soluble factor required for B cell maturation and survival. BAFF-R signals via the non-canonical NF-κB pathway regulated by the TRAF3/NIK/IKK1 axis. We show that deletion of Ikk1 during early B cell development causes a partial impairment in B cell maturation and BAFF-dependent survival, b...

Cijeli opis

Spremljeno u:
Bibliografski detalji
Glavni autori: Jellusova, Julia, Miletic, Ana V., Cato, Matthew H., Lin, Wai-Wai, Hu, Yinling, Bishop, Gail A., Shlomchik, Mark J., Rickert, Robert C.
Format: Artigo
Jezik:Inglês
Izdano: 2013
Teme:
Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3887557/
https://ncbi.nlm.nih.gov/pubmed/24239354
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2013.10.022
Oznake: Dodaj oznaku
Bez oznaka, Budi prvi tko označuje ovaj zapis!

Similar Items