Context-specific BAFF-R signaling by the NF-κB and PI3K pathways

BAFF is a soluble factor required for B cell maturation and survival. BAFF-R signals via the non-canonical NF-κB pathway regulated by the TRAF3/NIK/IKK1 axis. We show that deletion of Ikk1 during early B cell development causes a partial impairment in B cell maturation and BAFF-dependent survival, b...

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Detalhes bibliográficos
Main Authors: Jellusova, Julia, Miletic, Ana V., Cato, Matthew H., Lin, Wai-Wai, Hu, Yinling, Bishop, Gail A., Shlomchik, Mark J., Rickert, Robert C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3887557/
https://ncbi.nlm.nih.gov/pubmed/24239354
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2013.10.022
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