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Chemical Suppression of Defects in Mitotic Spindle Assembly, Redox Control, and Sterol Biosynthesis by Hydroxyurea

We describe the results of a systematic search for a class of hitherto-overlooked chemical-genetic interactions in the Saccharomyces cerevisiae genome, which exists between a detrimental genetic mutation and a chemical/drug that can ameliorate, rather than exacerbate, that detriment. We refer to thi...

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Détails bibliographiques
Auteurs principaux: McCulley, Andrew, Haarer, Brian, Viggiano, Susan, Karchin, Joshua, Feng, Wenyi
Format: Artigo
Langue:Inglês
Publié: Genetics Society of America 2013
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3887538/
https://ncbi.nlm.nih.gov/pubmed/24192836
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/g3.113.009100
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