Monoamine Oxidase B Prompts Mitochondrial and Cardiac Dysfunction in Pressure Overloaded Hearts

Aims: Monoamine oxidases (MAOs) are mitochondrial flavoenzymes responsible for neurotransmitter and biogenic amines catabolism. MAO-A contributes to heart failure progression via enhanced norepinephrine catabolism and oxidative stress. The potential pathogenetic role of the isoenzyme MAO-B in cardia...

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Main Authors: Kaludercic, Nina, Carpi, Andrea, Nagayama, Takahiro, Sivakumaran, Vidhya, Zhu, Guangshuo, Lai, Edwin W., Bedja, Djahida, De Mario, Agnese, Chen, Kevin, Gabrielson, Kathleen L., Lindsey, Merry L., Pacak, Karel, Takimoto, Eiki, Shih, Jean C., Kass, David A., Di Lisa, Fabio, Paolocci, Nazareno
Format: Artigo
Language:Inglês
Published: Mary Ann Liebert, Inc. 2014
Subjects:
Forum Original Research CommunicationsMitochondria (A. Daiber, Ed.)
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3887464/
https://ncbi.nlm.nih.gov/pubmed/23581564
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/ars.2012.4616
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