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Ceramides and Glucosylceramides Are Independent Antagonists of Insulin Signaling
Inhibitors of sphingolipid synthesis protect mice from diet induced-insulin resistance, and sphingolipids such as ceramides and glucosylated-ceramides (e.g., GM3) are putative nutritional intermediates linking obesity to diabetes risk. Herein we investigated the role of each of these sphingolipids i...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3887200/ https://ncbi.nlm.nih.gov/pubmed/24214972 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.522847 |
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