β-Arrestin Promotes Wnt-induced Low Density Lipoprotein Receptor-related Protein 6 (Lrp6) Phosphorylation via Increased Membrane Recruitment of Amer1 Protein

β-Arrestin is a scaffold protein that regulates signal transduction by seven transmembrane-spanning receptors. Among other functions it is also critically required for Wnt/β-catenin signal transduction. In the present study we provide for the first time a mechanistic basis for the β-arrestin functio...

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Bibliographische Detailangaben
Hauptverfasser: Kříž, Vítězslav, Pospíchalová, Vendula, Mašek, Jan, Kilander, Michaela Brita Christina, Slavík, Josef, Tanneberger, Kristina, Schulte, Gunnar, Machala, Miroslav, Kozubík, Alois, Behrens, Juergen, Bryja, Vítězslav
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2014
Schlagworte:
Cell Biology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3887180/
https://ncbi.nlm.nih.gov/pubmed/24265322
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.498444
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