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Amer1/WTX couples Wnt-induced formation of PtdIns(4,5)P(2) to LRP6 phosphorylation

Phosphorylation of the Wnt receptor low-density lipoprotein receptor-related protein 6 (LRP6) by glycogen synthase kinase 3β (GSK3β) and casein kinase 1γ (CK1γ) is a key step in Wnt/β-catenin signalling, which requires Wnt-induced formation of phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P(2))....

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Detalhes bibliográficos
Main Authors: Tanneberger, Kristina, Pfister, Astrid S, Brauburger, Katharina, Schneikert, Jean, Hadjihannas, Michel V, Kriz, Vitezslav, Schulte, Gunnar, Bryja, Vitezslav, Behrens, Jürgen
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3102280/
https://ncbi.nlm.nih.gov/pubmed/21304492
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2011.28
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