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Targeted Cytotoxic Therapy Kills Persisting HIV Infected Cells During ART

Antiretroviral therapy (ART) can reduce HIV levels in plasma to undetectable levels, but rather little is known about the effects of ART outside of the peripheral blood regarding persistent virus production in tissue reservoirs. Understanding the dynamics of ART-induced reductions in viral RNA (vRNA...

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Autori principali: Denton, Paul W., Long, Julie M., Wietgrefe, Stephen W., Sykes, Craig, Spagnuolo, Rae Ann, Snyder, Olivia D., Perkey, Katherine, Archin, Nancie M., Choudhary, Shailesh K., Yang, Kuo, Hudgens, Michael G., Pastan, Ira, Haase, Ashley T., Kashuba, Angela D., Berger, Edward A., Margolis, David M., Garcia, J. Victor
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3887103/
https://ncbi.nlm.nih.gov/pubmed/24415939
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1003872
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