Targeted Cytotoxic Therapy Kills Persisting HIV Infected Cells During ART

Antiretroviral therapy (ART) can reduce HIV levels in plasma to undetectable levels, but rather little is known about the effects of ART outside of the peripheral blood regarding persistent virus production in tissue reservoirs. Understanding the dynamics of ART-induced reductions in viral RNA (vRNA...

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Main Authors: Denton, Paul W., Long, Julie M., Wietgrefe, Stephen W., Sykes, Craig, Spagnuolo, Rae Ann, Snyder, Olivia D., Perkey, Katherine, Archin, Nancie M., Choudhary, Shailesh K., Yang, Kuo, Hudgens, Michael G., Pastan, Ira, Haase, Ashley T., Kashuba, Angela D., Berger, Edward A., Margolis, David M., Garcia, J. Victor
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2014
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3887103/
https://ncbi.nlm.nih.gov/pubmed/24415939
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1003872
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