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Colorectal Tumors from APC*I1307K Carriers Principally Harbor Somatic APC Mutations outside the A8 Tract

PURPOSE: APC*I1307K (c.3920T>A) is an inherited variant associated with colorectal tumour risk found almost exclusively in those of Ashkenazi Jewish ancestry. A single nucleotide substitution creates an oligo-adenine tract (A8) that appears to be inherently prone to further mis-pairing and slippa...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Zauber, Peter, Bishop, Timothy, Taylor, Claire, Sabbath-Solitare, Marlene, Marotta, Stephen, Tomlinson, Ian
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Public Library of Science 2014
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC3886998/
https://ncbi.nlm.nih.gov/pubmed/24416237
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0084498
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