Allosteric mechanism for codon-dependent tRNA selection on ribosomes.

We suggest that the interaction between a codon and its cognate tRNA induces conformational changes in the tRNA. We further suggest that sites on the ribosome preferentially bind tRNA in those conformations which require proper matching of codon and anticodon. According to this model, the codon func...

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Bibliographic Details
Main Authors: Kurland, C G, Rigler, R, Ehrenberg, M, Blomberg, C
Format: Artigo
Language:Inglês
Published: 1975
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC388697/
https://ncbi.nlm.nih.gov/pubmed/1060103
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