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The binding sites for tRNA on eukaryotic ribosomes.

We have studied the non-enzymic binding of phe-tRNA to ribosomes from rat liver using deacylated tRNA to inhibit binding to the P-site and puromycin (5 x 10-minus3M) to inhibit binding to the A-site. We conclude that at a low concentration of magnesium ions (10mM) phe-tRNA is bound only at the A-sit...

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Detalhes bibliográficos
Main Authors: Leader, D P, Machray, G C
Formato: Artigo
Idioma:Inglês
Publicado em: 1975
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC343504/
https://ncbi.nlm.nih.gov/pubmed/1098024
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