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PHOS-Select Iron Affinity beads enrich peptides for detection of organophosphorus adducts on albumin
Albumin is covalently modified by organophosphorus toxicants (OP) on tyrosine 411, but less than 1% of albumin is modified in humans by lethal OP doses that inhibit 95% of plasma butyrylcholinesterase. A method that enriches OP-modified albumin peptides could aid analysis of low dose exposures. Soma...
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| Главные авторы: | , , , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2013
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3886839/ https://ncbi.nlm.nih.gov/pubmed/24187955 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/tx400352h |
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