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In Vivo and In Vitro Evidence Supporting a Role for the Inflammatory Cytokine Interleukin-1 as a Driving Force in Alzheimer Pathogenesis

Interleukin-1 (IL-1), an inflammatory cytokine overexpressed in the neuritic plaques of Alzheimer’s disease, activates astrocytes and enhances production and processing of (β-amyloid precursor protein (β-APP). Activated astrocytes, overexpressing S100β, are a prominent feature of these neuritic plaq...

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Bibliografiske detaljer
Main Authors: SHENG, JIN G., ITO, KAZUHIRO, SKINNER, ROBERT D., MRAK, ROBERT E., ROVNAGHI, CYNTHIA R., VAN ELDIK, LINDA J., GRIFFIN, W. SUE T.
Format: Artigo
Sprog:Inglês
Udgivet: 1996
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3886636/
https://ncbi.nlm.nih.gov/pubmed/8892349
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