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In Vivo and In Vitro Evidence Supporting a Role for the Inflammatory Cytokine Interleukin-1 as a Driving Force in Alzheimer Pathogenesis
Interleukin-1 (IL-1), an inflammatory cytokine overexpressed in the neuritic plaques of Alzheimer’s disease, activates astrocytes and enhances production and processing of (β-amyloid precursor protein (β-APP). Activated astrocytes, overexpressing S100β, are a prominent feature of these neuritic plaq...
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| Hauptverfasser: | , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
1996
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3886636/ https://ncbi.nlm.nih.gov/pubmed/8892349 |
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