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Identification of a novel mono-leucine basolateral sorting motif within the cytoplasmic domain of amphiregulin

Epithelial cells establish apical and basolateral (BL) membranes with distinct protein and lipid compositions. To achieve this spatial asymmetry, the cell utilizes a variety of mechanisms for differential sorting, delivery and retention of cell surface proteins. The EGF receptor (EGFR) and its ligan...

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Détails bibliographiques
Auteurs principaux: Gephart, Jonathan D., Singh, Bhuminder, Higginbotham, James N., Franklin, Jeffrey L., Gonzalez, Alfonso, Fölsch, Heike, Coffey, Robert J.
Format: Artigo
Langue:Inglês
Publié: 2011
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3886124/
https://ncbi.nlm.nih.gov/pubmed/21917092
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1600-0854.2011.01282.x
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