Induction of lateral lumens through disruption of a monoleucine-based basolateral-sorting motif in betacellulin

Directed delivery of EGF receptor (EGFR) ligands to the apical or basolateral surface is a crucial regulatory step in the initiation of EGFR signaling in polarized epithelial cells. Herein, we show that the EGFR ligand betacellulin (BTC) is preferentially sorted to the basolateral surface of polariz...

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Bibliografiska uppgifter
I publikationen:J Cell Sci
Huvudupphovsmän: Singh, Bhuminder, Bogatcheva, Galina, Starchenko, Alina, Sinnaeve, Justine, Lapierre, Lynne A., Williams, Janice A., Goldenring, James R., Coffey, Robert J.
Materialtyp: Artigo
Språk:Inglês
Publicerad: The Company of Biologists 2015
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4582402/
https://ncbi.nlm.nih.gov/pubmed/26272915
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.170852
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