Induction of lateral lumens through disruption of a monoleucine-based basolateral-sorting motif in betacellulin

Directed delivery of EGF receptor (EGFR) ligands to the apical or basolateral surface is a crucial regulatory step in the initiation of EGFR signaling in polarized epithelial cells. Herein, we show that the EGFR ligand betacellulin (BTC) is preferentially sorted to the basolateral surface of polariz...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:J Cell Sci
Egile Nagusiak: Singh, Bhuminder, Bogatcheva, Galina, Starchenko, Alina, Sinnaeve, Justine, Lapierre, Lynne A., Williams, Janice A., Goldenring, James R., Coffey, Robert J.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: The Company of Biologists 2015
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4582402/
https://ncbi.nlm.nih.gov/pubmed/26272915
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.170852
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