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Mechanism of Inhibition of Bacillus subtilis DNA Polymerase III by the Arylhydrazinopyrimidine Antimicrobial Agents

Arylhydrazinopyrimidines inhibit DNA synthesis in Bacillus subtilis by promoting formation of a specific, long-lived ternary complex with DNA polymerase III and the template-primer DNA. DNA polymerase III contains an associated, single-strand-selective exonuclease which generates 5′-mononucleotides....

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Bibliografiske detaljer
Main Authors: Low, Robert L., Rashbaum, Stephan A., Cozzarelli, Nicholas R.
Format: Artigo
Sprog:Inglês
Udgivet: 1974
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC388601/
https://ncbi.nlm.nih.gov/pubmed/4213240
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