Mechanism of Inhibition of Bacillus subtilis DNA Polymerase III by the Arylhydrazinopyrimidine Antimicrobial Agents

Arylhydrazinopyrimidines inhibit DNA synthesis in Bacillus subtilis by promoting formation of a specific, long-lived ternary complex with DNA polymerase III and the template-primer DNA. DNA polymerase III contains an associated, single-strand-selective exonuclease which generates 5′-mononucleotides....

Full description

Saved in:
Bibliographic Details
Main Authors: Low, Robert L., Rashbaum, Stephan A., Cozzarelli, Nicholas R.
Format: Artigo
Language:Inglês
Published: 1974
Subjects:
Biological Sciences: Biochemistry
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC388601/
https://ncbi.nlm.nih.gov/pubmed/4213240
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items