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PD-L1 expression in the Merkel cell carcinoma microenvironment: Association with inflammation, Merkel cell polyomavirus and overall survival

Merkel cell carcinoma (MCC) is a lethal, virus-associated cancer that lacks effective therapies for advanced disease. Agents blocking the PD-1/PD-L1 pathway have demonstrated objective, durable tumor regressions in patients with advanced solid malignancies and efficacy has been linked to PD-L1 expre...

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Autors principals: Lipson, Evan J., Vincent, Jeremy G., Loyo, Myriam, Kagohara, Luciane T., Luber, Brandon S., Wang, Hao, Xu, Haiying, Nayar, Suresh K., Wang, Timothy S., Sidransky, David, Anders, Robert A., Topalian, Suzanne L., Taube, Janis M.
Format: Artigo
Idioma:Inglês
Publicat: 2013
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3885978/
https://ncbi.nlm.nih.gov/pubmed/24416729
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2326-6066.CIR-13-0034
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