Basal cell carcinoma: PD-L1/PD-1 checkpoint expression and tumor regression after PD-1 blockade

Monoclonal antibodies that block immune regulatory proteins such as programmed death-1 (PD-1) have demonstrated remarkable efficacy in controlling the growth of multiple tumor types. Unresectable or metastatic basal cell carcinoma, however, has largely gone untested. Because PD-Ligand-1 (PD-L1) expr...

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Detalhes bibliográficos
Publicado no:J Immunother Cancer
Main Authors: Lipson, Evan J., Lilo, Mohammed T., Ogurtsova, Aleksandra, Esandrio, Jessica, Xu, Haiying, Brothers, Patricia, Schollenberger, Megan, Sharfman, William H., Taube, Janis M.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
Assuntos:
Short Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5360064/
https://ncbi.nlm.nih.gov/pubmed/28344809
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40425-017-0228-3
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