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The antimalarial drug quinine interferes with serotonin biosynthesis and action

The major antimalarial drug quinine perturbs uptake of the essential amino acid tryptophan, and patients with low plasma tryptophan are predisposed to adverse quinine reactions; symptoms of which are similar to indications of tryptophan depletion. As tryptophan is a precursor of the neurotransmitter...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Islahudin, Farida, Tindall, Sarah M., Mellor, Ian R., Swift, Karen, Christensen, Hans E. M., Fone, Kevin C. F., Pleass, Richard J., Ting, Kang-Nee, Avery, Simon V.
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: Nature Publishing Group 2014
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3885885/
https://ncbi.nlm.nih.gov/pubmed/24402577
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep03618
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