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The Effects of Hemin and Double-Stranded RNA on α and β Globin Synthesis in Reticulocyte and Krebs II Ascites Cell-Free Systems and the Relationship of These Effects to an Initiation Factor Preparation

Protein synthesis in reticulocyte lysates ceases abruptly in the absence of added hemin or in the presence of double-stranded RNA. A similar effect of double-stranded RNA is observed in Krebs II ascites cell-free systems translating exogenous globin mRNA. The shut-off of protein synthesis is due to...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Beuzard, Yves, London, Irving M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 1974
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC388572/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4528029/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.71.7.2863
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