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Correcting the Cystic Fibrosis Disease Mutant, A455E CFTR

Cystic fibrosis is caused by more than 1000 mutations, the most common being the ΔF508 mutation. These mutations have been divided into five classes [1], with ΔF508 CFTR in class II. Here we have studied the class V mutation A455E. We report that the mature and immature bands of A455E are rapidly de...

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Bibliographische Detailangaben
Hauptverfasser: Cebotaru, Liudmila, Rapino, Daniele, Cebotaru, Valeriu, Guggino, William B.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3885674/
https://ncbi.nlm.nih.gov/pubmed/24416359
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0085183
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