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Correcting the Cystic Fibrosis Disease Mutant, A455E CFTR

Cystic fibrosis is caused by more than 1000 mutations, the most common being the ΔF508 mutation. These mutations have been divided into five classes [1], with ΔF508 CFTR in class II. Here we have studied the class V mutation A455E. We report that the mature and immature bands of A455E are rapidly de...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Cebotaru, Liudmila, Rapino, Daniele, Cebotaru, Valeriu, Guggino, William B.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Public Library of Science 2014
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3885674/
https://ncbi.nlm.nih.gov/pubmed/24416359
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0085183
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