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AAV gene therapy for cystic fibrosis: current barriers and recent developments

INTRODUCTION: Since the CF gene was discovered in 1989, researchers have worked to develop a gene therapy. One of the most promising and enduring vectors is AAV, which has been shown to be safe. In particular, several clinical trials have been conducted with AAV serotype 2. All of them detected vira...

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Detalles Bibliográficos
Publicado en:Expert Opin Biol Ther
Main Authors: Guggino, William B., Cebotaru, Liudmila
Formato: Artigo
Idioma:Inglês
Publicado: 2017
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5858933/
https://ncbi.nlm.nih.gov/pubmed/28657358
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/14712598.2017.1347630
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