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AAV gene therapy for cystic fibrosis: current barriers and recent developments

INTRODUCTION: Since the CF gene was discovered in 1989, researchers have worked to develop a gene therapy. One of the most promising and enduring vectors is AAV, which has been shown to be safe. In particular, several clinical trials have been conducted with AAV serotype 2. All of them detected vira...

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Bibliografiske detaljer
Udgivet i:Expert Opin Biol Ther
Main Authors: Guggino, William B., Cebotaru, Liudmila
Format: Artigo
Sprog:Inglês
Udgivet: 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5858933/
https://ncbi.nlm.nih.gov/pubmed/28657358
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/14712598.2017.1347630
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