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Targeting an Achilles’ heel of cancer with a WRN helicase inhibitor
Our recently published work suggests that DNA helicases such as the Werner syndrome helicase (WRN) represent a novel class of proteins to target for anticancer therapy. Specifically, pharmacological inhibition of WRN helicase activity in human cells defective in the Fanconi anemia (FA) pathway of in...
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Main Authors: | , , , |
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Formáid: | Artigo |
Teanga: | Inglês |
Foilsithe: |
Landes Bioscience
2013
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Ábhair: | |
Rochtain Ar Líne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3885643/ https://ncbi.nlm.nih.gov/pubmed/24036544 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.26320 |
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