Llwytho...

Delineation of WRN Helicase Function with EXO1 in the Replicational Stress Response

The WRN gene defective in the premature aging disorder Werner syndrome encodes a helicase/exonuclease. We examined the ability of WRN to rescue DNA damage sensitivity of a yeast mutant defective in the Rad50 subunit of Mre11-Rad50- Xrs2 nuclease complex implicated in homologous recombination repair....

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Aggarwal, Monika, Sommers, Joshua A., Morris, Christa, Brosh, Robert M.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2010
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2893289/
https://ncbi.nlm.nih.gov/pubmed/20447876
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2010.03.014
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