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Targeting an Achilles’ heel of cancer with a WRN helicase inhibitor
Our recently published work suggests that DNA helicases such as the Werner syndrome helicase (WRN) represent a novel class of proteins to target for anticancer therapy. Specifically, pharmacological inhibition of WRN helicase activity in human cells defective in the Fanconi anemia (FA) pathway of in...
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| Main Authors: | , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Landes Bioscience
2013
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3885643/ https://ncbi.nlm.nih.gov/pubmed/24036544 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.26320 |
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