Aesculetin suppresses proliferation of human colon cancer cells by directly targeting β-catenin

The Wnt pathway is a promising therapeutic and preventive target in various human cancers. The transcriptional complex of β-catenin/Tcf, a key mediator of canonical Wnt signaling, has been implicated in human colon cancer development. Current treatment of colon cancer depends on traditional cytotoxi...

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Bibliographic Details
Main Authors: Lee, Sung-Young, Lim, Tae-Gyu, Chen, Hanyong, Jung, Sung Keun, Lee, Hyo-Jeong, Lee, Mee-Hyun, Kim, Dong Joon, Shin, Aram, Lee, Ki Won, Bode, Ann M., Surh, Young-Joon, Dong, Zigang
Format: Artigo
Language:Inglês
Published: 2013
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3885338/
https://ncbi.nlm.nih.gov/pubmed/24104353
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1940-6207.CAPR-13-0241
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