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6,7,4′-Trihydroxyisoflavone inhibits HCT-116 human colon cancer cell proliferation by targeting CDK1 and CDK2

Colon cancer is a common epithelial malignancies worldwide. Epidemiologic evidence has shown that nutrition and dietary components are important environmental factors involved in the development of this disease. We investigated the biological activity of 6,7,4′-trihydroxyisoflavone (6,7,4′-THIF, a m...

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Detalhes bibliográficos
Main Authors: Lee, Dong Eun, Lee, Ki Won, Jung, Sung Keun, Lee, Eun Jung, Hwang, Jung A., Lim, Tae-Gyu, Kim, Bo Yeon, Bode, Ann M., Lee, Hyong Joo, Dong, Zigang
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3066420/
https://ncbi.nlm.nih.gov/pubmed/21258042
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgr008
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