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6,7,4′-Trihydroxyisoflavone inhibits HCT-116 human colon cancer cell proliferation by targeting CDK1 and CDK2

Colon cancer is a common epithelial malignancies worldwide. Epidemiologic evidence has shown that nutrition and dietary components are important environmental factors involved in the development of this disease. We investigated the biological activity of 6,7,4′-trihydroxyisoflavone (6,7,4′-THIF, a m...

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Autors principals: Lee, Dong Eun, Lee, Ki Won, Jung, Sung Keun, Lee, Eun Jung, Hwang, Jung A., Lim, Tae-Gyu, Kim, Bo Yeon, Bode, Ann M., Lee, Hyong Joo, Dong, Zigang
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2011
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3066420/
https://ncbi.nlm.nih.gov/pubmed/21258042
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgr008
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