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Contaminating levels of zinc found in commonly-used labware and buffers affect glycine receptor currents

Zinc is an allosteric modulator of glycine receptor function, enhancing the effects of glycine at nM to low μM concentrations, and inhibiting its effects at higher concentrations. Because of zinc’s high potency at the glycine receptor, there exists a possibility that effects attributed solely to exo...

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Autori principali: Cornelison, Garrett L., Mihic, S. John
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3885322/
https://ncbi.nlm.nih.gov/pubmed/24177173
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.brainresbull.2013.10.012
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